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Synthesis and Molecular Docking Study of New Thiazole Derivatives as Potential Tubulin Polymerization Inhibitors
[Image: see text] A new series of 2,4-disubstituted thiazole derivatives containing 4-(3,4,5-trimethoxyphenyl) moiety was synthesized and evaluated for their potential anticancer activity as tubulin polymerization inhibitors. All designed compounds were screened for cytotoxic activity against four h...
Autores principales: | El-Abd, Azhar O., Bayomi, Said M., El-Damasy, Ashraf K., Mansour, Basem, Abdel-Aziz, Naglaa I., El-Sherbeny, Magda A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9494671/ https://www.ncbi.nlm.nih.gov/pubmed/36157722 http://dx.doi.org/10.1021/acsomega.2c05077 |
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