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Nicotinamide reverses deficits in puberty-born neurons and cognitive function after maternal separation

BACKGROUND: Early life stress (ELS) is associated with the development of schizophrenia later in life. The hippocampus develops significantly during childhood and is extremely reactive to stress. In rodent models, ELS can induce neuroinflammation, hippocampal neuronal loss, and schizophrenia-like be...

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Detalles Bibliográficos
Autores principales: Hao, Keke, Wang, Huiling, Zhang, Yuejin, Xie, Xinhui, Huang, Huan, Chen, Cheng, Xu, Shilin, Xu, Rui, Shu, Chang, Liu, Zhongchun, Zhou, Yuan, Reynolds, Gavin P., Wang, Gaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9494869/
https://www.ncbi.nlm.nih.gov/pubmed/36131290
http://dx.doi.org/10.1186/s12974-022-02591-y