COX-2 Expression in Hepatocytes Improves Mitochondrial Function after Hepatic Ischemia-Reperfusion Injury

Cyclooxygenase 2 (COX-2) is a key enzyme in prostanoid biosynthesis. The constitutive hepatocyte expression of COX-2 has a protective role in hepatic ischemia-reperfusion (I/R) injury (IRI), decreasing necrosis, reducing reactive oxygen species (ROS) levels, and increasing autophagy and antioxidant...

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Detalles Bibliográficos
Autores principales: Fuertes-Agudo, Marina, Luque-Tévar, María, Cucarella, Carme, Brea, Rocío, Boscá, Lisardo, Quintana-Cabrera, Rubén, Martín-Sanz, Paloma, Casado, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495319/
https://www.ncbi.nlm.nih.gov/pubmed/36139798
http://dx.doi.org/10.3390/antiox11091724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495319/
https://www.ncbi.nlm.nih.gov/pubmed/36139798
http://dx.doi.org/10.3390/antiox11091724

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