Targeted Protein Degradation to Overcome Resistance in Cancer Therapies: PROTAC and N-Degron Pathway

Extensive progress in understanding the molecular mechanisms of cancer growth and proliferation has led to the remarkable development of drugs that target cancer-driving molecules. Most target molecules are proteins such as kinases and kinase-associated receptors, which have enzymatic activities nee...

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Detalles Bibliográficos
Autores principales: Kim, Hanbyeol, Park, Jeongbae, Kim, Jeong-Mok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495352/
https://www.ncbi.nlm.nih.gov/pubmed/36140200
http://dx.doi.org/10.3390/biomedicines10092100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495352/
https://www.ncbi.nlm.nih.gov/pubmed/36140200
http://dx.doi.org/10.3390/biomedicines10092100

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