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pH-Dependent Compaction of the Intrinsically Disordered Poly-E Motif in Titin

SIMPLE SUMMARY: The importance of pH shifts in biological systems is often underappreciated, but they can be a common form of regulation by both activating and inactivating important proteins. Proteins without any regular structure, commonly referred to as intrinsically disordered proteins, are very...

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Detalles Bibliográficos
Autores principales: Manukian, Sophia, Lindberg, Gerrick E., Punch, Emily, Mudiyanselage, Sudarshi Premawardhana Dassanayake, Gage, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495361/
https://www.ncbi.nlm.nih.gov/pubmed/36138781
http://dx.doi.org/10.3390/biology11091302