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A Riboswitch-Driven Era of New Antibacterials

Riboswitches are structured non-coding RNAs found in the 5′ UTR of important genes for bacterial metabolism, virulence and survival. Upon the binding of specific ligands that can vary from simple ions to complex molecules such as nucleotides and tRNAs, riboswitches change their local and global mRNA...

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Detalles Bibliográficos
Autores principales: Giarimoglou, Nikoleta, Kouvela, Adamantia, Maniatis, Alexandros, Papakyriakou, Athanasios, Zhang, Jinwei, Stamatopoulou, Vassiliki, Stathopoulos, Constantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495366/
https://www.ncbi.nlm.nih.gov/pubmed/36140022
http://dx.doi.org/10.3390/antibiotics11091243