Mitochondrial Glrx2 Knockout Augments Acetaminophen-Induced Hepatotoxicity in Mice

Acetaminophen (APAP) is one of the most widely used drugs with antipyretic and analgesic effects, and thus hepatotoxicity from the overdose of APAP becomes one of the most common forms of drug-induced liver injury. The reaction towards thiol molecules, such as GSH by APAP metabolite, N-acetyl-p-benz...

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Detalles Bibliográficos
Autores principales: Li, Jing, Tang, Xuewen, Wen, Xing, Ren, Xiaoyuan, Zhang, Huihui, Du, Yatao, Lu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495392/
https://www.ncbi.nlm.nih.gov/pubmed/36139718
http://dx.doi.org/10.3390/antiox11091643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495392/
https://www.ncbi.nlm.nih.gov/pubmed/36139718
http://dx.doi.org/10.3390/antiox11091643

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