Cargando…

Mitochondrial Glrx2 Knockout Augments Acetaminophen-Induced Hepatotoxicity in Mice

Acetaminophen (APAP) is one of the most widely used drugs with antipyretic and analgesic effects, and thus hepatotoxicity from the overdose of APAP becomes one of the most common forms of drug-induced liver injury. The reaction towards thiol molecules, such as GSH by APAP metabolite, N-acetyl-p-benz...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Jing, Tang, Xuewen, Wen, Xing, Ren, Xiaoyuan, Zhang, Huihui, Du, Yatao, Lu, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495392/ https://www.ncbi.nlm.nih.gov/pubmed/36139718 http://dx.doi.org/10.3390/antiox11091643

Ejemplares similares

Mitochondrial–Lysosomal Axis in Acetaminophen Hepatotoxicity
por: Moles, Anna, et al.
Publicado: (2018)

Silymarin prevents acetaminophen-induced hepatotoxicity in mice
por: Papackova, Zuzana, et al.
Publicado: (2018)

Redox Regulator GLRX Is Associated With Tumor Immunity in Glioma
por: Chang, Yuanhao, et al.
Publicado: (2020)

Redox Nanoparticle Therapeutics for Acetaminophen-Induced Hepatotoxicity in Mice
por: Boonruamkaew, Phetcharat, et al.
Publicado: (2016)

Chitohexaose protects against acetaminophen-induced hepatotoxicity in mice
por: Barman, P K, et al.
Publicado: (2016)

Fructose diet alleviates acetaminophen-induced hepatotoxicity in mice
por: Cho, Sungjoon, et al.
Publicado: (2017)

Calcitriol Protects against Acetaminophen-Induced Hepatotoxicity in Mice
por: Sriphoosanaphan, Supachaya, et al.
Publicado: (2023)

Protective Effects of Apamin on Acetaminophen-Induced Hepatotoxicity in Mice
por: Jang, Hyo-Jeong, et al.
Publicado: (2023)

Impact of malnourishment on the pharmacokinetics of acetaminophen and susceptibility to acetaminophen hepatotoxicity
por: Zillen, Daan, et al.
Publicado: (2021)

An Amino Acids Mixture Improves the Hepatotoxicity Induced by Acetaminophen in Mice
por: Di Pierro, Francesco, et al.
Publicado: (2013)

Sasa veitchii extracts suppress acetaminophen-induced hepatotoxicity in mice
por: Yoshioka, Hiroki, et al.
Publicado: (2017)

Evaluation of the Protective Effects of Doxycycline on Acetaminophen-Induced Hepatotoxicity in Mice
por: Soltani, Shirin, et al.
Publicado: (2019)

Role of Pyroptosis in Acetaminophen-Induced Hepatotoxicity
por: Jaeschke, Hartmut, et al.
Publicado: (2022)

Regeneration and Recovery after Acetaminophen Hepatotoxicity
por: Bhushan, Bharat, et al.
Publicado: (2023)

Acetaminophen Hepatotoxicity: Not as Simple as One Might Think! Introductory Comments on the Special Issue—Recent Advances in Acetaminophen Hepatotoxicity
por: Jaeschke, Hartmut
Publicado: (2022)

Effects of α-Melanocortin Enantiomers on Acetaminophen-Induced Hepatotoxicity in CBA Mice
por: Turčić, Petra, et al.
Publicado: (2009)

Characteristics and Outcomes of Acetaminophen Overdose and Hepatotoxicity in Thailand
por: Pholmoo, Natthiya, et al.
Publicado: (2019)

Mechanisms of acetaminophen hepatotoxicity and their translation to the human pathophysiology
por: Ramachandran, Anup, et al.
Publicado: (2017)

Acetaminophen-Induced Hepatotoxicity: a Comprehensive Update
por: Yoon, Eric, et al.
Publicado: (2016)

Possible Role of Extracellular Vesicles in Hepatotoxicity of Acetaminophen
por: Šrajer Gajdošik, Martina, et al.
Publicado: (2022)

Fluorine-thiol displacement probes for acetaminophen's hepatotoxicity
por: Prather, Benjamin L., et al.
Publicado: (2023)

Hepatoprotective and Antioxidative Activities of Cornus officinalis against Acetaminophen-Induced Hepatotoxicity in Mice
por: Lee, Nam-Hun, et al.
Publicado: (2012)

IRE1α activation protects mice against acetaminophen-induced hepatotoxicity
por: Hur, Kyu Yeon, et al.
Publicado: (2012)

Attenuating Oxidative Stress by Paeonol Protected against Acetaminophen-Induced Hepatotoxicity in Mice
por: Ding, Yi, et al.
Publicado: (2016)

Protective Effects of Interleukin-37 Expression against Acetaminophen-Induced Hepatotoxicity in Mice
por: Xu, Zhiwei, et al.
Publicado: (2022)

The biochemistry of acetaminophen hepatotoxicity and rescue: a mathematical model
por: Ben-Shachar, Rotem, et al.
Publicado: (2012)

Altered responsiveness to extracellular ATP enhances acetaminophen hepatotoxicity
por: Amaral, Sylvia S, et al.
Publicado: (2013)

Emerging novel therapies against paracetamol (acetaminophen) hepatotoxicity
por: Jaeschke, Hartmut
Publicado: (2019)

The Glutaredoxin GLRX-21 Functions to Prevent Selenium-Induced Oxidative Stress in Caenorhabditis elegans
por: Morgan, Kathleen L., et al.
Publicado: (2010)

Peroxynitrite formation and sinusoidal endothelial cell injury during acetaminophen-induced hepatotoxicity in mice
por: Knight, Tamara R, et al.
Publicado: (2004)

Study of the Protective Effect of Teucrium polium L. Extract on Acetaminophen-Induced Hepatotoxicity in Mice
por: Forouzandeh, Hossein, et al.
Publicado: (2013)

Protective effects of natsumikan (Citrus natsudaidai) extract on acetaminophen-induced lethal hepatotoxicity in mice
por: Yamaura, Katsunori, et al.
Publicado: (2012)

Protective Effect of Gemfibrozil on Hepatotoxicity Induced by Acetaminophen in Mice: the Importance of Oxidative Stress Suppression
por: Nikravesh, Hojatolla, et al.
Publicado: (2018)

The Ameliorative Effects of l-2-Oxothiazolidine-4-Carboxylate on Acetaminophen-Induced Hepatotoxicity in Mice
por: Choi, Jiwon, et al.
Publicado: (2013)

Aryl Hydrocarbon Receptor Activity in Hepatocytes Sensitizes to Hyperacute Acetaminophen-Induced Hepatotoxicity in Mice
por: Schuran, Fenja A., et al.
Publicado: (2020)

Targeting IKKβ Activity to Limit Sterile Inflammation in Acetaminophen-Induced Hepatotoxicity in Mice
por: Kim, Song-Hee, et al.
Publicado: (2023)

Essential Involvement of Neutrophil Elastase in Acute Acetaminophen Hepatotoxicity Using BALB/c Mice
por: Ishida, Yuko, et al.
Publicado: (2023)

Flavokawains A and B in Kava, Not Dihydromethysticin, Potentiate Acetaminophen-Induced Hepatotoxicity in C57BL/6 Mice
por: Narayanapillai, Sreekanth C., et al.
Publicado: (2014)

Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential
por: Du, Kuo, et al.
Publicado: (2016)

CXCL5 Promotes Acetaminophen-Induced Hepatotoxicity by Activating Kupffer Cells
por: Qiu, Kexin, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_srb6igfe8711bb0m5dgtdgut1i