Rice Nudix Hydrolase OsNUDX2 Sanitizes Oxidized Nucleotides

Nudix hydrolase (NUDX) hydrolyzes 8-oxo-(d)GTP to reduce the levels of oxidized nucleotides in the cells. 8-oxo-(d)GTP produced by reactive oxygen species (ROS) is incorporated into DNA/RNA and mispaired with adenine, causing replicational and transcriptional errors. Here, we identified a rice OsNUD...

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Detalles Bibliográficos
Autores principales: Kondo, Yuki, Rikiishi, Kazuhide, Sugimoto, Manabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495418/
https://www.ncbi.nlm.nih.gov/pubmed/36139879
http://dx.doi.org/10.3390/antiox11091805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495418/
https://www.ncbi.nlm.nih.gov/pubmed/36139879
http://dx.doi.org/10.3390/antiox11091805

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