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Icariside II Exerts Anti-Type 2 Diabetic Effect by Targeting PPARα/γ: Involvement of ROS/NF-κB/IRS1 Signaling Pathway

Type 2 diabetes mellitus (T2DM) is a multisystem and complex metabolic disorder which is associated with insulin resistance and impairments of pancreatic β-cells. Previous studies have shown that icariside II (ICS II), one of the main active ingredients of Herba Epimedii, exerts potent anti-inflamma...

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Detalles Bibliográficos
Autores principales: Li, Yiqi, Li, Yeli, Chen, Nana, Feng, Linying, Gao, Jianmei, Zeng, Nan, He, Zhixu, Gong, Qihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495514/
https://www.ncbi.nlm.nih.gov/pubmed/36139776
http://dx.doi.org/10.3390/antiox11091705