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NADPH Oxidase Mediates Oxidative Stress and Ventricular Remodeling through SIRT3/FOXO3a Pathway in Diabetic Mice

Oxidative stress and mitochondrial dysfunction are important mechanisms of ventricular remodeling, predisposed to the development of diabetic cardiomyopathy (DCM) in type 2 diabetes mellitus. In this study, we have successfully established a model of type 2 diabetes using a high-fat diet (HFD) in co...

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Detalles Bibliográficos
Autores principales: Qiu, Jiuchun, Liu, Daiqi, Li, Pengsha, Zhou, Lingling, Zhou, Lu, Liu, Xing, Zhang, Yue, Yuan, Meng, Tse, Gary, Li, Guangping, Liu, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495652/
https://www.ncbi.nlm.nih.gov/pubmed/36139819
http://dx.doi.org/10.3390/antiox11091745