Suppression of NRF2 Activity by HIF-1α Promotes Fibrosis after Ischemic Acute Kidney Injury

Acute kidney injury (AKI) is a rapid decline in renal function and can occur after ischemia/reperfusion injury (IRI) to the tubular epithelia. The nuclear factor erythroid-2-related factor 2 (NRF2) pathway protects against AKI and AKI-to-chronic kidney disease (CKD) progression, but we previously de...

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Detalles Bibliográficos
Autores principales: Bondi, Corry D., Rush, Brittney M., Hartman, Hannah L., Wang, Jiaxuan, Al-Bataineh, Mohammad M., Hughey, Rebecca P., Tan, Roderick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495756/
https://www.ncbi.nlm.nih.gov/pubmed/36139884
http://dx.doi.org/10.3390/antiox11091810

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495756/
https://www.ncbi.nlm.nih.gov/pubmed/36139884
http://dx.doi.org/10.3390/antiox11091810

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