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Suppression of NRF2 Activity by HIF-1α Promotes Fibrosis after Ischemic Acute Kidney Injury
Acute kidney injury (AKI) is a rapid decline in renal function and can occur after ischemia/reperfusion injury (IRI) to the tubular epithelia. The nuclear factor erythroid-2-related factor 2 (NRF2) pathway protects against AKI and AKI-to-chronic kidney disease (CKD) progression, but we previously de...
Autores principales: | Bondi, Corry D., Rush, Brittney M., Hartman, Hannah L., Wang, Jiaxuan, Al-Bataineh, Mohammad M., Hughey, Rebecca P., Tan, Roderick J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495756/ https://www.ncbi.nlm.nih.gov/pubmed/36139884 http://dx.doi.org/10.3390/antiox11091810 |
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