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Intrarenal Arterial Transplantation of Dexmedetomidine Preconditioning Adipose Stem-Cell-Derived Microvesicles Confers Further Therapeutic Potential to Attenuate Renal Ischemia/Reperfusion Injury through miR-122-5p/Erythropoietin/Apoptosis Axis

Intravenous adipose mesenchymal stem cells (ADSCs) attenuate renal ischemia/reperfusion (IR) injury but with major drawbacks, including the lack of a specific homing effect after systemic infusion, cell trapping in the lung, and early cell death in the damaged microenvironment. We examined whether i...

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Detalles Bibliográficos
Autores principales: Cheng, Yu-Hsuan, Chen, Kuo-Hsin, Sung, Yi-Ting, Yang, Chih-Ching, Chien, Chiang-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495781/
https://www.ncbi.nlm.nih.gov/pubmed/36139786
http://dx.doi.org/10.3390/antiox11091702