De Novo Self-Assembling Peptides Mediate the Conversion of Temozolomide and Delivery of a Model Drug into Glioblastoma Multiforme Cells

Glioblastoma multiforme (GBM) is the most aggressive central nervous system tumor, and standard treatment, including surgical resection, radiation, and chemotherapy, has not significantly improved patient outcomes over the last 20 years. Temozolomide (TMZ), the prodrug most commonly used to treat GB...

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Detalles Bibliográficos
Autores principales: Pitz, Megan, Elpers, Margaret, Nukovic, Alexandra, Wilde, Sarah, Gregory, Arica Jordan, Alexander-Bryant, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495814/
https://www.ncbi.nlm.nih.gov/pubmed/36140265
http://dx.doi.org/10.3390/biomedicines10092164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495814/
https://www.ncbi.nlm.nih.gov/pubmed/36140265
http://dx.doi.org/10.3390/biomedicines10092164

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