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Multi-Functionalized Heteroduplex Antisense Oligonucleotides for Targeted Intracellular Delivery and Gene Silencing in HeLa Cells

Oligonucleotide therapeutics, antisense oligonucleotides (ASOs) and short interfering RNA (siRNA) are short synthetic nucleic acid molecules with a promising potential to treat a wide range of diseases. Despite considerable progress in the field, the development of safe and effective delivery system...

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Detalles Bibliográficos
Autores principales: Sousa de Almeida, Mauro, Rothen-Rutishauser, Barbara, Mayer, Michael, Taskova, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495875/
https://www.ncbi.nlm.nih.gov/pubmed/36140196
http://dx.doi.org/10.3390/biomedicines10092096