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Multi-Functionalized Heteroduplex Antisense Oligonucleotides for Targeted Intracellular Delivery and Gene Silencing in HeLa Cells
Oligonucleotide therapeutics, antisense oligonucleotides (ASOs) and short interfering RNA (siRNA) are short synthetic nucleic acid molecules with a promising potential to treat a wide range of diseases. Despite considerable progress in the field, the development of safe and effective delivery system...
Autores principales: | Sousa de Almeida, Mauro, Rothen-Rutishauser, Barbara, Mayer, Michael, Taskova, Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495875/ https://www.ncbi.nlm.nih.gov/pubmed/36140196 http://dx.doi.org/10.3390/biomedicines10092096 |
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