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Hepatic damage caused by long-term high cholesterol intake induces a dysfunctional restorative macrophage population in experimental NASH

Excessive dietary cholesterol is preferentially stored in the liver, favoring the development of nonalcoholic steatohepatitis (NASH), characterized by progressive hepatic inflammation and fibrosis. Emerging evidence indicates a critical contribution of hepatic macrophages to NASH severity. However,...

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Detalles Bibliográficos
Autores principales: Maretti-Mira, Ana C., Salomon, Matthew P., Hsu, Angela M., Kanel, Gary C., Golden-Mason, Lucy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495937/
https://www.ncbi.nlm.nih.gov/pubmed/36159810
http://dx.doi.org/10.3389/fimmu.2022.968366