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Dissecting the Activity of Catechins as Incomplete Aldose Reductase Differential Inhibitors through Kinetic and Computational Approaches

SIMPLE SUMMARY: The increased glucose levels occurring in diabetes lead to several metabolic alterations responsible for the onset of the so-called diabetic complications, which include nephropathies, neuropathies, retinopathies, and cataract. An increased flux of glucose through the polyol pathway...

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Detalles Bibliográficos
Autores principales: Balestri, Francesco, Poli, Giulio, Piazza, Lucia, Cappiello, Mario, Moschini, Roberta, Signore, Giovanni, Tuccinardi, Tiziano, Mura, Umberto, Del Corso, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495972/
https://www.ncbi.nlm.nih.gov/pubmed/36138801
http://dx.doi.org/10.3390/biology11091324