The Activation of Nrf2/HO-1 by 8-Epi-7-deoxyloganic Acid Attenuates Inflammatory Symptoms through the Suppression of the MAPK/NF-κB Signaling Cascade in In Vitro and In Vivo Models

In this study, we examined the ameliorative effects of 8-epi-7-deoxyloganic acid (DLA), an iridoid glycoside, on oxidative stress and inflammation in both LPS-stimulated macrophages and mice with carrageenan-induced inflammation. DLA decreased oxidative stress through the up-regulation of heme oxyge...

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Detalles Bibliográficos
Autores principales: Simu, Shakina Yesmin, Alam, Md Badrul, Kim, Sun Yeou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495988/
https://www.ncbi.nlm.nih.gov/pubmed/36139839
http://dx.doi.org/10.3390/antiox11091765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495988/
https://www.ncbi.nlm.nih.gov/pubmed/36139839
http://dx.doi.org/10.3390/antiox11091765

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