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Synuclein Proteins in MPTP-Induced Death of Substantia Nigra Pars Compacta Dopaminergic Neurons

Parkinson’s disease (PD) is one of the key neurodegenerative disorders caused by a dopamine deficiency in the striatum due to the death of dopaminergic (DA) neurons of the substantia nigra pars compacta. The initially discovered A53T mutation in the alpha-synuclein gene was linked to the formation o...

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Detalles Bibliográficos
Autores principales: Goloborshcheva, Valeria V., Kucheryanu, Valerian G., Voronina, Natalia A., Teterina, Ekaterina V., Ustyugov, Aleksey A., Morozov, Sergei G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496024/
https://www.ncbi.nlm.nih.gov/pubmed/36140378
http://dx.doi.org/10.3390/biomedicines10092278