Antitumor Effect of Brusatol in Acute Lymphoblastic Leukemia Models Is Triggered by Reactive Oxygen Species Accumulation

Acute lymphoblastic leukemia (ALL) is one of the most common hematological malignancies at pediatric ages and is characterized by different chromosomal rearrangements and genetic abnormalities involved in the differentiation and proliferation of lymphoid precursor cells. Brusatol is a quassinoid pla...

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Detalles Bibliográficos
Autores principales: Jorge, Joana, Magalhães, Nisa, Alves, Raquel, Lapa, Beatriz, Gonçalves, Ana Cristina, Sarmento-Ribeiro, Ana Bela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496058/
https://www.ncbi.nlm.nih.gov/pubmed/36140308
http://dx.doi.org/10.3390/biomedicines10092207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496058/
https://www.ncbi.nlm.nih.gov/pubmed/36140308
http://dx.doi.org/10.3390/biomedicines10092207

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