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MicroRNAs Involved in Intrinsic Apoptotic Pathway during Cisplatin-Induced Nephrotoxicity: Potential Use of Natural Products against DDP-Induced Apoptosis

Cisplatin (cis-diamminedichloroplatinum (II), DDP) is an antineoplastic agent widely used in the treatment of solid tumors because of its extensive cytotoxic activity. However, the main limiting side effect of DDP use is nephrotoxicity, a rapid deterioration in kidney function due to toxic chemicals...

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Detalles Bibliográficos
Autores principales: Loren, Pía, Lugones, Yuliannis, Saavedra, Nicolás, Saavedra, Kathleen, Páez, Isis, Rodriguez, Nelia, Moriel, Patricia, Salazar, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496062/
https://www.ncbi.nlm.nih.gov/pubmed/36139046
http://dx.doi.org/10.3390/biom12091206