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Apoptosis Detection in Retinal Ganglion Cells Using Quantitative Changes in Multichannel Fluorescence Colocalization

KcapTR488 is a dual-fluorophore peptide sensor for the real-time reporting of programmed cell death by fluorescence imaging. KcapTR488 contains a nuclear localization sequence (NLS) conjugated with Texas Red, a caspase-cleavable sequence (DEVD), and a C-terminus conjugated to Alexa Fluor 488 (AF488)...

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Detalles Bibliográficos
Autores principales: Qiu, Xudong, Gammon, Seth T., Johnson, James R., Pisaneschi, Federica, Millward, Steven W., Barnett, Edward M., Piwnica-Worms, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496076/
https://www.ncbi.nlm.nih.gov/pubmed/36140078
http://dx.doi.org/10.3390/bios12090693