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The Post-Translational Modification Networking in WNK-Centric Hypertension Regulation and Electrolyte Homeostasis

The with-no-lysine (WNK) kinase family, comprising four serine-threonine protein kinases (WNK1-4), were first linked to hypertension due to their mutations in association with pseudohypoaldosteronism type II (PHAII). WNK kinases regulate crucial blood pressure regulators, SPAK/OSR1, to mediate the p...

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Detalles Bibliográficos
Autores principales: Lin, Shiuan-Chen, Ma, Chun, Chang, Kao-Jung, Cheong, Han-Ping, Lee, Ming-Cheng, Lan, Yuan-Tzu, Wang, Chien-Ying, Chiou, Shih-Hwa, Huo, Teh-Ia, Hsu, Tsui-Kang, Tsai, Ping-Hsing, Yang, Yi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496095/
https://www.ncbi.nlm.nih.gov/pubmed/36140271
http://dx.doi.org/10.3390/biomedicines10092169