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The Post-Translational Modification Networking in WNK-Centric Hypertension Regulation and Electrolyte Homeostasis
The with-no-lysine (WNK) kinase family, comprising four serine-threonine protein kinases (WNK1-4), were first linked to hypertension due to their mutations in association with pseudohypoaldosteronism type II (PHAII). WNK kinases regulate crucial blood pressure regulators, SPAK/OSR1, to mediate the p...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496095/ https://www.ncbi.nlm.nih.gov/pubmed/36140271 http://dx.doi.org/10.3390/biomedicines10092169 |