Recent Advances of Degradation Technologies Based on PROTAC Mechanism

PROTAC (proteolysis-targeting chimeras), which selectively degrades target proteins, has become the most popular technology for drug development in recent years. Here, we introduce the history of PROTAC, and summarize the recent advances in novel types of degradation technologies based on the PROTAC...

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Detalles Bibliográficos
Autores principales: Xiao, Mingchao, Zhao, Jiaojiao, Wang, Qiang, Liu, Jia, Ma, Leina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496103/
https://www.ncbi.nlm.nih.gov/pubmed/36139095
http://dx.doi.org/10.3390/biom12091257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496103/
https://www.ncbi.nlm.nih.gov/pubmed/36139095
http://dx.doi.org/10.3390/biom12091257

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