Functional and Structural Impact of Deleterious Missense Single Nucleotide Polymorphisms in the NR3C1, CYP3A5, and TNF-α Genes: An In Silico Analysis

Human diseases are generally influenced by SNPs (single nucleotide polymorphisms). The mutations in amino acid residues generated by deleterious SNPs contribute to the structural and functional diversity of the encoded protein. Tumor necrosis factor-α (TNF-α), Glucocorticoid receptor gene (NR3C1), a...

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Detalles Bibliográficos
Autores principales: Ramayanam, Navakanth Raju, Manickam, Ranjani, Mahalingam, Vijayakumar Thangavel, Goh, Khang Wen, Ardianto, Chrismawan, Ganesan, Poovi, Ming, Long Chiau, Ganesan, Rajanandh Muhasaparur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496109/
https://www.ncbi.nlm.nih.gov/pubmed/36139147
http://dx.doi.org/10.3390/biom12091307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496109/
https://www.ncbi.nlm.nih.gov/pubmed/36139147
http://dx.doi.org/10.3390/biom12091307

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