Small Molecules as Toll-like Receptor 4 Modulators Drug and In-House Computational Repurposing

The innate immunity toll-like receptor 4 (TLR4) system is a receptor of paramount importance as a therapeutic target. Virtual screening following a “computer-aided drug repurposing” approach was applied to the discovery of novel TLR4 modulators with a non-lipopolysaccharide-like structure. We screen...

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Detalles Bibliográficos
Autores principales: Pérez-Regidor, Lucía, Guzmán-Caldentey, Joan, Oberhauser, Nils, Punzón, Carmen, Balogh, Balázs, Pedro, José R., Falomir, Eva, Nurisso, Alessandra, Mátyus, Péter, Menéndez, J. Carlos, de Andrés, Belén, Fresno, Manuel, Martín-Santamaría, Sonsoles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496124/
https://www.ncbi.nlm.nih.gov/pubmed/36140427
http://dx.doi.org/10.3390/biomedicines10092326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496124/
https://www.ncbi.nlm.nih.gov/pubmed/36140427
http://dx.doi.org/10.3390/biomedicines10092326

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