Calcium Overload or Underload? The Effects of Doxorubicin on the Calcium Dynamics in Guinea Pig Hearts

The severe doxorubicin (DOXO) side effect of cardiomyopathy limits it clinical application as an effective anticancer drug. Although Ca(2+) overload was postulated as one of the mechanisms for this toxicity, its role was, however, disputable in terms of the contractile dysfunction. In this work, the...

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Detalles Bibliográficos
Autores principales: Wu, Jingjing, Gao, Linlin, Fan, Hong, Liu, Deming, Lin, Mengxue, Zhu, Ming, Deng, Tian, Song, Yuanlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496179/
https://www.ncbi.nlm.nih.gov/pubmed/36140298
http://dx.doi.org/10.3390/biomedicines10092197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496179/
https://www.ncbi.nlm.nih.gov/pubmed/36140298
http://dx.doi.org/10.3390/biomedicines10092197

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