Renal Metabolome in Obese Mice Treated with Empagliflozin Suggests a Reduction in Cellular Respiration

Sodium glucose cotransporter, type 2 inhibitors, such as Empagliflozin, are protective of the kidneys by unclear mechanisms. Our aim was to determine how Empagliflozin affected kidney cortical metabolome and lipidome in mice. Adult male TALLYHO mice (prone to obesity) were treated with a high-milk-f...

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Detalles Bibliográficos
Autores principales: Bangarbale, Surabhi, Shepard, Blythe D., Bansal, Shivani, Jayatilake, Meth M., Kurtz, Ryan, Levi, Moshe, Ecelbarger, Carolyn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496198/
https://www.ncbi.nlm.nih.gov/pubmed/36139016
http://dx.doi.org/10.3390/biom12091176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496198/
https://www.ncbi.nlm.nih.gov/pubmed/36139016
http://dx.doi.org/10.3390/biom12091176

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