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Renal Metabolome in Obese Mice Treated with Empagliflozin Suggests a Reduction in Cellular Respiration
Sodium glucose cotransporter, type 2 inhibitors, such as Empagliflozin, are protective of the kidneys by unclear mechanisms. Our aim was to determine how Empagliflozin affected kidney cortical metabolome and lipidome in mice. Adult male TALLYHO mice (prone to obesity) were treated with a high-milk-f...
Autores principales: | Bangarbale, Surabhi, Shepard, Blythe D., Bansal, Shivani, Jayatilake, Meth M., Kurtz, Ryan, Levi, Moshe, Ecelbarger, Carolyn M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496198/ https://www.ncbi.nlm.nih.gov/pubmed/36139016 http://dx.doi.org/10.3390/biom12091176 |
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