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2-Hydroxypropyl-beta-cyclodextrin Treatment Does Not Induce Atherosclerotic Lesion Regression in Western-Type Diet-Fed Apolipoprotein E Knockout Mice

2-Hydroxypropyl-beta-cyclodextrin (2HPβCD) is able to bind and solubilize unesterified cholesterol and may therefore be able to reverse the deposition of cholesterol in macrophages within the aortic vessel wall, a hallmark of atherosclerotic cardiovascular disease. However, conflicting results regar...

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Detalles Bibliográficos
Autores principales: Snip, Olga S.C., Hoekstra, Menno, Zhang, Yiheng, Geerling, Janine J., Van Eck, Miranda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496214/
https://www.ncbi.nlm.nih.gov/pubmed/36139044
http://dx.doi.org/10.3390/biom12091205