Natural and Modified Oligonucleotide Sequences Show Distinct Strand Displacement Kinetics and These Are Affected Further by Molecular Crowders

DNA and RNA strand exchange is a process of fundamental importance in biology. Herein, we used a FRET-based assay to investigate, for the first time, the stand exchange kinetics of natural DNA, natural RNA, and locked nucleic acid (LNA)-modified DNA sequences in vitro in PBS in the absence or presen...

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Detalles Bibliográficos
Autores principales: Domljanovic, Ivana, Ianiro, Alessandro, Rüegg, Curzio, Mayer, Michael, Taskova, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496266/
https://www.ncbi.nlm.nih.gov/pubmed/36139087
http://dx.doi.org/10.3390/biom12091249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496266/
https://www.ncbi.nlm.nih.gov/pubmed/36139087
http://dx.doi.org/10.3390/biom12091249

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