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Controversial Role of Transferrin in the Transport of Ruthenium Anticancer Drugs

Ruthenium complexes are at the forefront of developments in metal-based anticancer drugs, but many questions remain open regarding their reactivity in biological media, including the role of transferrin (Tf) in their transport and cellular uptake. A well-known anticancer drug, KP1019 ((IndH)[Ru(III)...

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Detalles Bibliográficos
Autores principales: Levina, Aviva, Chetcuti, Anthony R. M., Lay, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496346/
https://www.ncbi.nlm.nih.gov/pubmed/36139158
http://dx.doi.org/10.3390/biom12091319