Cargando…

Residues in the 1st Transmembrane-Spanning Helix Are Important for GABA(A)ρ Receptor Function

GABA(A)ρ receptors are a subfamily of the GABA(A) receptor family of pentameric ligand-gated ion channels (pLGICs). Each subunit has a common structure, including a transmembrane domain of four α-helices (M1–M4). The aim of this study was to identify important M1 residues in the GABA(A)ρ receptor (G...

Descripción completa

Detalles Bibliográficos
Autores principales: Crowther, Kate M., Mesoy, Susanne M., Lummis, Sarah C. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496367/
https://www.ncbi.nlm.nih.gov/pubmed/36139090
http://dx.doi.org/10.3390/biom12091251