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Microglia Contributes to BAF-312 Effects on Blood–Brain Barrier Stability

Microglia, together with astrocytes and pericytes, cooperate to ensure blood–brain barrier (BBB) stability, modulating endothelial responses to inflammatory insults. Agonists of the sphingosine 1 phosphate (S1P) receptors, such as siponimod (BAF-312), are important pharmacological tools in multiple...

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Detalles Bibliográficos
Autores principales: Spampinato, Simona Federica, Costantino, Giuseppe, Merlo, Sara, Canonico, Pier Luigi, Sortino, Maria Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496388/
https://www.ncbi.nlm.nih.gov/pubmed/36139013
http://dx.doi.org/10.3390/biom12091174