The JAK1/2 Inhibitor Baricitinib Mitigates the Spike-Induced Inflammatory Response of Immune and Endothelial Cells In Vitro

The purpose of this study was to examine the effect of the JAK-STAT inhibitor baricitinib on the inflammatory response of human monocyte-derived macrophages (MDM) and endothelial cells upon exposure to the spike S1 protein from SARS-CoV-2. The effect of the drug has been evaluated on the release of...

Descripción completa

Detalles Bibliográficos
Autores principales: Barilli, Amelia, Visigalli, Rossana, Ferrari, Francesca, Recchia Luciani, Giulia, Soli, Maurizio, Dall’Asta, Valeria, Rotoli, Bianca Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496399/
https://www.ncbi.nlm.nih.gov/pubmed/36140425
http://dx.doi.org/10.3390/biomedicines10092324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496399/
https://www.ncbi.nlm.nih.gov/pubmed/36140425
http://dx.doi.org/10.3390/biomedicines10092324

Ejemplares similares