Integrin β1/Cell Surface GRP78 Complex Regulates TGFβ1 and Its Profibrotic Effects in Response to High Glucose

Diabetic kidney disease (DKD) is the leading cause of kidney failure worldwide. Characterized by overproduction and accumulation of extracellular matrix (ECM) proteins, glomerular sclerosis is its earliest manifestation. High glucose (HG) plays a central role by increasing matrix production by glome...

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Detalles Bibliográficos
Autores principales: Trink, Jackie, Li, Renzhong, Squire, Evan, O’Neil, Kian, Zheng, Phoebe, Gao, Bo, Krepinsky, Joan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496450/
https://www.ncbi.nlm.nih.gov/pubmed/36140347
http://dx.doi.org/10.3390/biomedicines10092247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496450/
https://www.ncbi.nlm.nih.gov/pubmed/36140347
http://dx.doi.org/10.3390/biomedicines10092247

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