The Anti-Aggregative Peptide KLVFF Mimics Aβ1-40 in the Modulation of Nicotinic Receptors: Implications for Peptide-Based Therapy

In recent years, the inhibition of beta-amyloid (Aβ) aggregation has emerged as a potential strategy for Alzheimer’s disease. KLVFF, a small peptide corresponding to the aminoacidic sequence 16-20 of Aβ, reduces Aβ fibrillation dose dependently. Therefore, the toxic and functional characterization o...

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Detalles Bibliográficos
Autores principales: Trebesova, Hanna, Olivero, Guendalina, Marchi, Mario, Grilli, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496455/
https://www.ncbi.nlm.nih.gov/pubmed/36140331
http://dx.doi.org/10.3390/biomedicines10092231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496455/
https://www.ncbi.nlm.nih.gov/pubmed/36140331
http://dx.doi.org/10.3390/biomedicines10092231

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