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Metoprolol Inhibits Developmental Brain Sterol Biosynthesis in Mice
De novo sterol synthesis is a critical homeostatic mechanism in the brain that begins during early embryonic development and continues throughout life. Multiple medications have sterol-biosynthesis-inhibiting side effects, with potentially detrimental effects on brain health. Using LC-MS/MS, we inve...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496459/ https://www.ncbi.nlm.nih.gov/pubmed/36139049 http://dx.doi.org/10.3390/biom12091211 |