4-OI Protects MIN6 Cells from Oxidative Stress Injury by Reducing LDHA-Mediated ROS Generation

Pancreatic beta cells are highly susceptible to oxidative stress, which plays a crucial role in diabetes outcomes. Progress has been slow to identify molecules that could be utilized to enhance cell survival and function under oxidative stress. Itaconate, a byproduct of the tricarboxylic acid cycle,...

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Detalles Bibliográficos
Autores principales: Wu, Jianmin, Gu, Xingshi, Zhang, Juan, Mi, Ze, He, Zhenhu, Dong, Yuqian, Ge, Wu, Ghimire, Kedar, Rong, Pengfei, Wang, Wei, Ma, Xiaoqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496514/
https://www.ncbi.nlm.nih.gov/pubmed/36139075
http://dx.doi.org/10.3390/biom12091236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496514/
https://www.ncbi.nlm.nih.gov/pubmed/36139075
http://dx.doi.org/10.3390/biom12091236

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