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Elucidation of the Correlation between Heme Distortion and Tertiary Structure of the Heme-Binding Pocket Using a Convolutional Neural Network

Heme proteins serve diverse and pivotal biological functions. Therefore, clarifying the mechanisms of these diverse functions of heme is a crucial scientific topic. Distortion of heme porphyrin is one of the key factors regulating the chemical properties of heme. Here, we constructed convolutional n...

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Detalles Bibliográficos
Autores principales: Kondo, Hiroko X., Iizuka, Hiroyuki, Masumoto, Gen, Kabaya, Yuichi, Kanematsu, Yusuke, Takano, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496533/
https://www.ncbi.nlm.nih.gov/pubmed/36139011
http://dx.doi.org/10.3390/biom12091172