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Building Protein Atomic Models from Cryo-EM Density Maps and Residue Co-Evolution

Electron cryo-microscopy (cryo-EM) has emerged as a powerful method by which to obtain three-dimensional (3D) structures of macromolecular complexes at atomic or near-atomic resolution. However, de novo building of atomic models from near-atomic resolution (3–5 Å) cryo-EM density maps is a challengi...

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Detalles Bibliográficos
Autores principales: Bouvier, Guillaume, Bardiaux, Benjamin, Pellarin, Riccardo, Rapisarda, Chiara, Nilges, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496541/
https://www.ncbi.nlm.nih.gov/pubmed/36139128
http://dx.doi.org/10.3390/biom12091290