Kynurenine 3-Monooxygenase Interacts with Huntingtin at the Outer Mitochondrial Membrane

The flavoprotein kynurenine 3-monooxygenase (KMO) is localised to the outer mitochondrial membrane and catalyses the synthesis of 3-hydroxykynurenine from L-kynurenine, a key step in the kynurenine pathway (KP) of tryptophan degradation. Perturbation of KP metabolism due to inflammation has long bee...

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Detalles Bibliográficos
Autores principales: Swaih, Aisha M., Breda, Carlo, Sathyasaikumar, Korrapati V., Allcock, Natalie, Collier, Mary E. W., Mason, Robert P., Feasby, Adam, Herrera, Federico, Outeiro, Tiago F., Schwarcz, Robert, Repici, Mariaelena, Giorgini, Flaviano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496550/
https://www.ncbi.nlm.nih.gov/pubmed/36140394
http://dx.doi.org/10.3390/biomedicines10092294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496550/
https://www.ncbi.nlm.nih.gov/pubmed/36140394
http://dx.doi.org/10.3390/biomedicines10092294

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