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Inflammation and Oxidative Stress Induce NGF Secretion by Pulmonary Arterial Cells through a TGF-β1-Dependent Mechanism

Expression of the nerve growth factor NGF is increased in pulmonary hypertension (PH). We have here studied whether oxidative stress and inflammation, two pathological conditions associated with transforming growth factor-β1 (TGF-β1) in PH, may trigger NGF secretion by pulmonary arterial (PA) cells....

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Detalles Bibliográficos
Autores principales: Bouchet, Clément, Cardouat, Guillaume, Douard, Matthieu, Coste, Florence, Robillard, Paul, Delcambre, Frédéric, Ducret, Thomas, Quignard, Jean-François, Vacher, Pierre, Baudrimont, Isabelle, Marthan, Roger, Berger, Patrick, Guibert, Christelle, Freund-Michel, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496672/
https://www.ncbi.nlm.nih.gov/pubmed/36139373
http://dx.doi.org/10.3390/cells11182795