MDMX Regulates Transcriptional Activity of p53 and FOXO Proteins to Stimulate Proliferation of Melanoma Cells

SIMPLE SUMMARY: We have investigated the transcriptional changes occurring in uveal and cutaneous melanoma cell lines upon depletion of MDMX (aka:MDM4). Computational analyses of the mRNAs/genes affected upon MDMX depletion determined that many were containing a p53-bindingsite, but even more contai...

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Detalles Bibliográficos
Autores principales: Heijkants, Renier C., Teunisse, Amina F. A. S., de Jong, Danielle, Glinkina, Kseniya, Mei, Hailiang, Kielbasa, Szymon M., Szuhai, Karoly, Jochemsen, Aart G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496676/
https://www.ncbi.nlm.nih.gov/pubmed/36139642
http://dx.doi.org/10.3390/cancers14184482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496676/
https://www.ncbi.nlm.nih.gov/pubmed/36139642
http://dx.doi.org/10.3390/cancers14184482

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