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Suppression of Hepatic PPARα in Primary Biliary Cholangitis Is Modulated by miR-155

Background: PPARα is a ligand-activated transcription factor that shows protective effects against metabolic disorders, inflammation and apoptosis. Primary biliary cholangitis and primary sclerosing cholangitis result in the intrahepatic accumulation of bile acids that leads to liver dysfunction and...

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Detalles Bibliográficos
Autores principales: Adamowicz, Monika, Kempinska-Podhorodecka, Agnieszka, Abramczyk, Joanna, Banales, Jesus M., Milkiewicz, Piotr, Milkiewicz, Malgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496720/
https://www.ncbi.nlm.nih.gov/pubmed/36139455
http://dx.doi.org/10.3390/cells11182880