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Role of Fe, Transferrin and Transferrin Receptor in Anti-Tumor Effect of Vitamin C

SIMPLE SUMMARY: High-dose vitamin C (VC) inhibits cell proliferation in a variety of tumors, which is mediated by ROS. Iron is an important factor in the Fenton reaction, in which H(2)O(2) reacts with ferrous iron to produce hydroxyl radicals, which may enhance the killing of tumor cells. In this st...

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Detalles Bibliográficos
Autores principales: Qiu, Jia, Wu, Renbo, Long, Yali, Peng, Lei, Yang, Tianhong, Zhang, Bing, Shi, Xinchong, Liu, Jianbo, Zhang, Xiangsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496724/
https://www.ncbi.nlm.nih.gov/pubmed/36139668
http://dx.doi.org/10.3390/cancers14184507