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Role of Fe, Transferrin and Transferrin Receptor in Anti-Tumor Effect of Vitamin C
SIMPLE SUMMARY: High-dose vitamin C (VC) inhibits cell proliferation in a variety of tumors, which is mediated by ROS. Iron is an important factor in the Fenton reaction, in which H(2)O(2) reacts with ferrous iron to produce hydroxyl radicals, which may enhance the killing of tumor cells. In this st...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496724/ https://www.ncbi.nlm.nih.gov/pubmed/36139668 http://dx.doi.org/10.3390/cancers14184507 |