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Insights into Epigenetic Changes Related to Genetic Variants and Cells-of-Origin of Pancreatic Neuroendocrine Tumors: An Algorithm for Practical Workup

SIMPLE SUMMARY: Pancreatic neuroendocrine tumors are composite entities due to their heterogeneity illustrated in clinical behavior, mutational pattern, and site of origin. Pancreatic neuroendocrine tumors display a low mutation burden with frequently epigenetic alterations, such as histone modifica...

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Detalles Bibliográficos
Autores principales: Ciobanu, Oana A., Martin, Sorina C., Herlea, Vlad, Fica, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496769/
https://www.ncbi.nlm.nih.gov/pubmed/36139607
http://dx.doi.org/10.3390/cancers14184444